Injectable Drug Development

Filled with strategies to minimize the adverse effects of injectable drugs this book provides the scientific background and techniques required to evaluate parenteral formulations with respect to their potential to cause pain irritation and muscle damage. Using a unique interdisciplinary approach the book's editors and contributors represent the areas of pharmaceutics physiology anatomy toxicology and product formulation. The chapters cover topics such as muscle damage with injectables in vitro and in vivo cystolic enzyme release histological and morphological methods assessing pain cosolvents in injectables biodegradable microparticles and more.