Interaction of Trypanosomatids with the Insect Vector

In the Americas two species of trypanosomes have a high incidence and medical importance: Trypanosoma cruzi and Trypanosoma rangeli. These two parasites use invertebrate hosts members of the Reduviidae family especially Rhodnius prolixus. During its life cycle T. rangeli crosses the intestinal epithelium and invades the insect's hemolymph while T. cruzi remains in the lumen of the vector's intestine. In the present study we demonstrate for the first time the uptake of lipophorin (Lp) which is the main lipid transport particle in the insect's hemolymph by these trypanosomes.