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The working principle of the colorimeter is based on Beer-Lamberts law which states that the amount of light absorbed by a color solution is directly proportional to the concentration of the solution and the length of a light path through the solution. Flame photometry can be used to measure Na+ K+ and lithium Li+ .This method is based on the fact that some metallic elements absorb thermal energy exciting their electrons to a higher energy state. Microscope instrument that produces enlarged images of small objects allowing the observer an exceedingly close view of minute structures at a scale convenient for examination and analysis. Different types of microscopes are explained with internal structures. The use of biosafety practices and principles to reduce the health-related risks associated with handling infectious agents toxins and other biological hazards is important in a laboratory setting. Spectrophotometry is a method to measure how much a chemical substance absorbs light by measuring the intensity of light as a beam of light passes through sample solution. The above cited equipments are explained clearly with figures and transducers Electronics circuits. Maintenance Repair and Trouble shooting charts are drawn.