β-lactams have received wide use as key synthons for many biologicallyimportant classes of compounds in organic synthesis. Especially the monocyclicβ -lactams namely azetidinones are an important part of theβ-lactams antibioticscaffold which are always obtained via classical Staudinger ketene-iminecycloaddition reaction and are known to exhibit interesting and broad biologicalactivities. A large number of monocyclic β-lactams possess powerfulantibacterial antimicrobial anti- inflammatory anti-convulsant anti-viral andantitubercular activities
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