This book constitutes the refereed proceedings of the 14th International Conference on&nbsp;Large-Scale Scientific Computations LSSC 2023 held in Sozopol Bulgaria during June 5���9 2023.&nbsp;<div><br></div><div>The 49 full papers included in this book were carefully reviewed and selected from 61 submissions. They were organized in topical sections as follows: preconditioning and multilevel methods; fractures and mixed dimensional modeling: discretizations solvers and methodology; machine learning and model order reduction for large scale predictive simulations; fractional differential problems: theoretical aspects algorithms and applications; variational analysis and optimal control; stochastic optimal control and numerical methods in economics and finance; tensor methods for big data analytics and low-rank approximations of PDEs solutions; applications of metaheuristics to large-scale problems; large-scale models: numerical methods parallel computations and applications;&nbsp;HPC and HPDA: algorithms and applications.</div>
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