<p>The coronavirus disease 2019 (COVID-19) has led to the worst worldwide healthcare outbreak of the current century. Our knowledge on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 virus) the agent causing COVID-19 has dramatically increased in recent years. Further healthcare systems are facing another outbreak due to COVID-19-long COVID or post-COVID-19 syndrome-which is the presence of long-lasting symptoms after an acute SARS-CoV-2 infection. The development of long-lasting post-COVID-19 symptoms has been called long COVID or a post-COVID-19 condition. To date more than 100 potential long-lasting post-COVID symptoms have been potentially attributed to SARS-CoV-2. This Special Issue of <em>Biomedicines</em> entitled Latest Research in Post-COVID-19 (long COVID-19): Pathological and Treatment Studies of Sequelae and Complications has focused on potential gaps in our knowledge regarding the identification timeframe mechanisms and treatment strategies for the management of the post-COVID-19 condition. The fourteen published papers in this Special Issue cover the following topics: 1 treatment of the post-COVID-19 condition; 2 neonatal repercussion of the SARS-CoV-2 infection; 3 risk factors of severe COVID-19; 4 phenotyping of post-COVID-19 pain; and 5 others.</p>
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