Metal Complexes of Mannich Base

The study of Mannich reaction attracted a great deal of attention to the chemist. Mannich base derivative with bridge N-atom and heterocyclic nucleus have been found to be potent drug and therapeutic application. Such as anti-bacterial anti-fungal anti-tumor anti-convulsant anti-inflammatory anti-malarial anti-biotic anti-viral anti-cancer and anti-leishmanial Mannich base also used in analgesic cytotoxic oxytocic anti-psychotic diuretic centrally active muscle relaxant and tranquilizer. It also employed as an intermediate in industrial chemical synthesis. It exhibit complexation characteristic with many transition metal ions. The Use of the Iso-nicotinic Acid Hydrazides in the Treatment of Tuberculosis. This book deals with the synthesis characterization of metal complexes using mannich base.