Mitochondrial dysfunction forms the basis of human diseases like neurodegeneration cancer autoimmune diseases schizophrenia bipolar affective disorder and diabetes mellitus. Mitochondrial drugs used to treat mitochondrial dysfunction include coenzyme Q carnitine vitamin E taurine NAD and D-glucosamine. A ketodiet high in fat and proteins and low in carbohydrate can stimulate mitochondrial function. The gut flora can digest dietary fibre generating butyrate a short chain fatty acid which stimulates mitochondrial function. A high fibre diet can produce mitochondrial stimulation. Dietary fibre is the elixir of life.