Modern approach to the treatment of patients with CHD

Cardiovascular disease is currently a key public health problem and the leading cause of death in developed countries. Epidemiologic studies confirm that an increased risk of coronary heart disease (CHD) and other manifestations of atherosclerosis is associated with increased blood cholesterol levels especially low-density lipoprotein (LDL). Atherosclerosis is based on abnormalities in lipid metabolism and transport as well as inflammation of the vascular wall. Treatment focuses on lowering bad cholesterol (LDL) and increasing anti-atherogenic lipoproteins. Statins HMG-CoA reductase inhibitors effectively lower cholesterol levels and are considered effective drugs for the prevention of cardiovascular complications. In light of these risks milk thistle which contains silymarin an antioxidant complex is of interest as a potential liver-protective agent. Silymarin may prevent liver cell damage regenerate damaged cells and enhance antioxidant defense. Studies show the effectiveness of milk thistle in treating various liver diseases including hepatitis and cirrhosis.