Molecular Analysis of Carbapenem Resistance

Antimicrobial resistance is a growing threat worldwide. The foundation of modern medicine is built on the availability of effective antibiotics especially in economically deprived areas of the world where the disease burden due to bacterial infections remain high. Antibiotic resistance is predominantly fueled by antibiotic use (Goossens et al.2005). With their broad spectrum activity for Gram-positives Gram- negatives and anaerobic bacteria carbapenems are frequently used as a last line of therapy.