This volume provides a compilation of the main principles of signal transduction mechanisms. The reader will become familiar with the most recent developments- the structure and function of heterotrimeric G-proteins and their receptors;- the small GTPases Ras Rho Rab and Arf;- EGF receptor Ca2+ and protein kinase C;- phosphoinositide kinases (PI-3 kinases);- phospholipases C and D;- ceramides and possible modulators of apoptosis;- transcription factors and gene activation;- multidrug resistance transporters.
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