mTOR Signaling in Metabolism and Cancer

The mechanistic/mammalian target of rapamycin (mTOR) a serine/threonine kinase is a central regulator for human physiological activity. Deregulated mTOR signaling is implicated in a variety of disorders such as cancer obesity diabetes and neurodegenerative diseases. The papers published in this Special Issue summarize the current understanding of the mTOR pathway and its role in the regulation of tissue regeneration regulatory T cell differentiation and function and different types of cancer including hematologic malignancies skin prostate breast and head and neck cancer. The findings highlight that targeting mTOR pathway is a promising strategy to fight against certain human diseases.