Nanoparticle-Based Drug Delivery in Cancer Treatment

<p>The careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. <b><i>Nanoparticle-Based Drug Delivery in Cancer</i></b> <b><i>Treatment</i></b> discusses nanotechnological developments of interfering RNA-based nanoparticles, delivery vehicles, and validated therapeutic RNAi–molecular target interactions and explains the results of clinical and preclinical trials. The book also gives strategies for universal methods of constructing hybrid organic–inorganic nanomaterials that can be widely applied in the biomedical field. </p><p>Key Features:</p><ul> <p> </p> <li>Reviews recent advances of nanoparticle-mediated siRNA delivery systems and their application in clinical trials for cancer therapy </li> <p> </p> <li>Focuses on material platforms that establish NPs and both localized and controlled gene silencing </li> <p> </p> <li>Emphasizes the most promising systems for clinical application</li> <p> </p> <li>Surveys progress in nanoparticle-based nanomedicine in cancer treatment</li> <p> </p> <li>Describes the most advanced of the nonviral nanocarriers for delivery of oligonucleotides to malignant blood cancer cells</li> </ul><p>This book is a valuable resource for researchers, professors, and students researching drug delivery, gene carriers, cancer therapy, nanotechnology, and nanomaterials.</p> <p>Chapter 01</p><p>The advantages and versatility of carrier—free nanodrugs and nanoparticles systems for cancer therapy</p><p>Chapter 02</p><p>Strategies, design, and chemistry in siRNA delivery vehicles systems for cancer therapy </p><p>Chapter 03</p><p>DNA/RNA nanoparticles structures for siRNA deliver applications</p><p>Chapter 04</p><p>Co-delivery in nanoparticle-based siRNA for cancer therapy</p><p>Chapter 05</p><p>Small interfering RNAs (siRNAs), MicroRNAs and NPs in gynecological cancers</p><p>Chapter 06</p><p>Nanoparticle–based RNA (siRNA) combination therapy toward overcoming drug resistance in cancer</p><p>Chapter 07</p><p>Imaging modalities delivery of RNAi therapeutics in cancer therapy and clinical applications</p><p>Chapter 08</p><p>Recent development of Silica nanoparticles as delivery biomedical applications for cancer imaging and therapy</p><p>Chapter 09</p><p>Application of carbon nanotubes (CNTs) in cancer vaccines as drug delivery tools</p><p>Chapter 10</p><p>Development of oligonucleotides delivery, (siRNAs), and (miRNA) systems for anticancer therapeutic strategy immunotherapy</p><p>Chapter 11</p><p>Pharmacogenomics-synergistic strategies using a chimerical peptide for enhanced chemotherapy based on ROS and DNA nanosystem</p><p>Chapter 12</p><p>Pharmacokinetics, biodistribution and therapeutic applications of recently-developed siRNA and DNA repair genes recurrence</p><p>Chapter 13</p><p>Nanotechnologies assemblies of siRNA and chemotherapeutic drugs co-delivered for cancer therapeutic applications</p><p>Chapter 14</p><p>Targeted systemic combinatorial delivery of siRNA polyplexes-Functional quantum dot-siRNA nanoplexes</p><p>Chapter 15</p><p>Recent advances of nanotechnologies for cancer immunotherapy treatment</p><p>List of Abbreviations</p>