Neisseria: Molecular Mechanisms of Pathogenesis

This important book provides research scientists advanced students clinicians and other professionals with a comprehensive update on the current understanding of the molecular mechanisms of pathogenesis in Neisseria. Neisseria gonorrhoeae and Nesseria meningitidis are Gram-negative diplococci. N. gonorrhoeae is the causative agent of gonorrhoeae and is transmitted via sexual contact. N. meningitidis is transmitted via respiratory droplets leading to colonization of the nasopharynx and can cause meningitis and septicemia. The book describes the latest up-to-date research theory and clinical significance of molecular mechanisms in meningococcal disease. Leading authorities have contributed chapters on topics such as gene expression genomics biofilms denitrification adhesion strategies and mechanisms of cellular invasion. A section on the host response to neisserial infection covers inate immunity complement apoptosis and acquired immunity while a section devoted to clinical correlation deals with vaccine development epidemiology and antibiotic resistance. The book is highly recommended for microbiologists epidemiologists and clinicians involved with Neisseria research or meningococcal disease and it is a recommended text for all microbiology libraries.