<p>The New Approaches to Synthetic Organic Chemistry Special Issue has continued to challenge and expand our scientific knowledge of the surrounding world exploring the frontiers between at least two of its dynamic interfaces: human life and the environment. Subject to all evolutionary facets of organic chemistry its perpetual developments reimagined within the current organic synthesis (strategies methodologies reaction mechanisms reagents catalysts chemical and instrumental auxiliaries) nevertheless obey two crucial common denominators selectivity vs. specificity (these terms being equally preceded by typical prefixes either chemo- regio- or stereo-) as mandatory criteria. The present Special Issue gathered research articles communications and review papers disclosing the most recent advances in organic synthesis i.e. those related to its near future defined as atomic precision in chemical reactions. The sustainability of these efforts which denotes an intrinsic chemical diversity is expected to highlight to the interested readers their innovative applications in human life and the environment.</p>
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