The benzoxazole nucleus is an important heterocyclic moiety and their derivatives display a wide variety of important biological activities such as antimicrobial anti-inflammatory anti-viral anti-histaminic herbicidal anthelmintic anti-cancer hypoglycemic 5-HT3 agonist diuretic and 5-HT3 antagonist uricosuric. The book covers much on the synthesis of few novel benzoxazole derivatives their characterization and biological / pharmacological evaluation.