Obesity; most common metabolic complication in Prader-Willi syndrome

Prader–Willi syndrome (PWS) is a genetic disorder due to loss of function of specific genes. In newborns symptoms include weak muscles poor feeding and slow development. Beginning in childhood the person becomes constantly hungry which often leads to obesity and type 2 diabetes. Also mild to moderate intellectual impairment and behavioural problems are typical. Often the forehead is narrow hands and feet are small height is short skin is light in colour and most of the affected are unable to have children.