Osseointegration

Osseointegration defined as a direct structural and functional connection between ordered living bone and the surface of a load-carrying implant is critical for implant stability and is considered a prerequisite for implant loading and long-term clinical success of end osseous dental implants. The implant–tissue interface is an extremely dynamic region of interaction. This complex interaction involves not only biomaterial and biocompatibility issues but also alteration of mechanical environment. The processes of osseointegration involve an initial interlocking between alveolar bone and the implant body and later biological fixation through continuous bone apposition and remodeling toward the implant. The process itself is quite complex and there are many factors that influence the formation and maintenance of bone at the implant surface.