Oxidative stress in Periodontology

Periodontitis is associated with hyperactivity of peripheral blood neutrophils which are supposed to be the predominant source of ROS. Products of lipid peroxidation protein damage and DNA damage can be used as the biomarkers of oxidative stress associated with periodontitis. Local and systemic activities of antioxidants can also be influenced by periodontitis. Over the past few years numerous clinical and basic experimental studies have shown a strong association between oxidative stress and periodontitis. Therefore understanding of this association can give us a deeper insight into the pathogenesis of periodontitis relationship between periodontitis and systemic inflammation and therapeutic strategies.