Periapex: Sanctum Sanctorum of Endodontics

The importance of a thorough knowledge of the periapex lies in the fact that the challenges involved in the treatment of this obscure and unclear area seem to be infinite. Not only do the apices of certain teeth bear close association with important structures like maxillary sinus and inferior alveolar nerve leading to serious clinical implications but it also known that the anatomic variations and complexities of the apical third of the root result in various mechanical challenges for effective and efficient management during endodontic therapy.