The health and economic devastation caused by COVID-19 shows that health systems in many countries cannot cope with pandemics and this challenge calls for global responses.“PESTEL Implications of COVID-19” examines risks and opportunities associated with the pandemic to proffer solutions based on the fundamentals of global strategic thinking. The author analysed COVID-related political economic social technological environmental and legal events in the US UK and EU Member Countries to demonstrate how a company should change and adapt its domestic business model to achieve a competitive advantage as it expands globally.At the heart of this book is a bold new proposal for stakeholders in the global health ecosystem to collaborate towards creating early warning systems preparedness prevention responses and containment.