Azoles are characterized by high physiological activities. Five membered heterocycles incorporating two heteroatoms of which one must be nitrogen are called as azoles e.g. pyrazoles imidazoles benzimidazoles thiazoles thiadiazoles oxazoles oxadiazoles triazoles tetrazoles. These have been exploited in designing drugs and pesticides.Nitrogen containing azoles are well known for their versatile biological activities. Derivatives of pyrazoles imidazoles benzimidazoles triazoles and tetrazoles possess fungicidal and herbicidal activities.Several heterocyclic compounds incorporating oxygen and nitrogen in the ring and possessing fungicidal144 bactericidal herbicidal antiviral and other activities are oxazoles isooxazoles benzoxazoles oxadiazoles and oxazolidinones.The heterocyclic systems incorporating nitrogen and sulphur atoms display a wide range of biocidal activities and a large number of such compounds have been developed as useful pesticidal agents. Most important ring systems of these types are thiazoles benzothiazoles thiadiazoles and thiazolidinones.
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