PI3K/AKT/mTOR Signaling Network in Human Health and Diseases

<p><span style=color: rgba(23 43 77 1)>In recent years researchers have shown a special interest in the role of signaling pathways as disease molecular targets and capitalized on such pathways to derive natural products biologics and synthetic scaffold-based prevention and treatments. These can lead to naturally available efficacious low-cost and minimally toxic long-term therapies for human diseases. This Special Issue of </span><em style=color: rgba(23 43 77 1)>Cells</em><span style=color: rgba(23 43 77 1)> comprises an array of literature reviews original communications and studies on the roles of the PI3K/AKT/mTOR and associated pathways in a diversity of pathways using in vitro cell-based assays and preclinical animal models. The authors of the papers also explore technologies designed to improve the bioavailability and delivery of certain compounds. In lieu of ongoing research on a variety of human disorders the wealth of information published in this Special Issue can act as a springboard for the identification of novel disease targets and the development of new preventive and therapeutic modalities for the management of human diseases.</span></p>