Post-allogeneic hematopoietic transplant complications

Our study showed that for the adult population the most costly complications were chronic GVH CMV infections and febrile neutropenia. Analysis of drug treatment costs showed that drugs account for the lion's share of direct medical costs after hematopoietic stem cell (HSC) allograft transplantation. Antifungals (Fluconazole Voriconazole) account for 50% of total costs antivirals (Aciclovir Valaciclovir Ganciclovir) represent around 26% of total costs mainly used for the prevention of CMV infections and immunosuppressants (Ciclosporin Tacrolimus) make up 6% of expenditure.