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About The Book
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<p>This practical book is intended for use in B. Pharmacy and Pharm D courses on medicinal chemistry. It mainly consists experiments as per PCI regulations. It provides a suitable background for graduates in chemistry who are just entering the pharmaceutical industry. This practical manual has been written not only to enhance students understanding of chemistry but also to capture data and take observations. In this book introduction to medicinal chemistry safety measures to be taken basic equipment and instrumentation was described. In Part A according to the PCI syllabus synthesis of compounds has been described clearly starting from the aim requirements principle procedure and calculations. The schemes and the reactions involved in the synthetic procedure were described. Followed by Assay of some compounds i.e. percentage purity of marketed compounds and the analytical techniques was discussed. Partition coefficient of benzoic acid and paracetamol was discussed. Determination of physiochemical properties and drawing of drugs structures was discussed along with the synthesis and assays of given compounds in Part B.</p>
<p> The practical manual provides the newly qualified graduates with an understanding of new developments as they take place in future years. Any suggestions for future development of the book are most welcome and will be highly appreciated.</p>