In December 2019 the world was hit by an unprecedented pandemic. At the origin of this one a virus of the family of Coronaviridae; the SARS-COV-2 responsible for a new pathology affecting the human respiratory system: the Coronavirus disease also called COVID-19. The rapid spread of the disease worldwide has caused a major international health and economic crisis. Many studies are underway to eradicate this disease. The genomic sequencing of SARS-COV-2 has revealed numerous mutations in its genome particularly in its surface glycoprotein: protein S or SPIKE (Pic).The present study consisted in determining the prevalence of SARS-COV-2 variants in COVID-19 positive individuals in Bamako Mali.
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