Psoriasis treatment

Non-biologic therapies are useful in psoriasis for intermittent rotational or combination treatment and in managing difficult to treat psoriasis patients with minimal lesions or who have achieved recommended cumulative dose or developed side effects/intolerance to conventional drugs or where co-morbidities pose unusual challenges. Methotrexate cyclosporine acitretin tar anthralin corticosteroids or calcipotriol ointments and phototherapy are well established in psoriasis treatment. Hydroxycarbamide azathioprine leflunomide mycophenolate mofetil isotretinoin fumarates calcineurin inhibitors peroxisome proliferator-activated receptor agonists statins pentoxifylline sulfasalazine colchicine or various physical modalities often mentioned as non-standard therapies. They will remain important until an affordable safe effective and remittiv therapy becomes available.