Revitalization procedures have helped to develop regenerative endodontics in the clinical scenario. In place of blood clot various natural and synthetic scaffolds are being tried like platelet- rich plasma platelet-rich fibrin or even the recently developed Nanofibrous and bioactive scaffolds. All this implies a highly evolving field. The introduction and implementation of these findings into clinical practice will definitely bring forth a positive influence on patient- centered outcomes in terms of disease resolution and rate of tooth survival.The innovations in technology the discovery of newer materials and medicaments and a better understanding of the principles of tissue engineering has all brought about a paradigm shift in the treatment of non-vitalized teeth. Moreover recent case reports from multiple investigators support the feasibility of developing biologically based revitalization in endodontic procedures designed to restore a functional pulp-dentin complex. In short the question is no longer whether the revitalization procedures can be successful insteadit is the issues that must be addressed to develop a safe effective and consistent method for regeneration.
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