Radiotracers in Drug Development

<p>Although there are numerous books on drug metabolism <b>Radiotracers in Drug Development</b> is unique in explaining how radiotracers are used to elucidate a drug’s absorption distribution metabolism and excretion (ADME). Covering traditional and recent technologies and applications the book takes a strong industrial approach discussing the basics of scintillation counting and untangling the various data processing methods often specific to individual manufacturers.</p><p>The chapters include descriptions of the latest micro-plate counters and the growing applications of accelerator mass spectrometry positron emission tomography gamma-scintigraphy and radioluminography. In addition to describing how the analytical technologies work the contributors explain how the data are interpreted and used in the drug registration process. </p><p>A unique reference and training aid essential for every drug metabolism department or drug metabolism research team the book provides insight into the use and practice of ADME in a way that is both instructive and practical. Moving easily across the boundaries of biology chemistry and physics this is the only comprehensive interdisciplinary resource covering the how-tos of employing radiotracers in drug development. It provides detailed information on how the science is relevant to the registration process.</p>