Rapidly Progressive Glomerulonephritis

Rapidly Progressive Glomerulonephritis is one of the most exciting areas in renal medicine. However appropriate immunosuppressive therapy can dramatically improve the prognosis in many cases such that renal failure is avoided. It is clear now that various immunopathological processes are involved and that an accurate diagnosis is of value in guiding management. This volume aims to bring together current knowledge of both scientific and clinical aspects of RPN. Recent advances in the immunology inflammatory mechanisms and pathology of RPGN are discussed. This is followed by consideration of the major causes of RPGN which include Goodpasture''s disease primary systematic vasculitis and systematic lupus erythematosus. RPGN secondary to other renal and systemic diseases and RPGN in children are also described. Finally new approaches to treatment are reviewed. Although certain of these areas are covered in the larger textbooks of renal medicine our aim is to provide a current overview of RPGN in a concise volume. This should be of particular interest to nephrologists and general physicians including those in training but may also be of value to pathologists immunologists and other studying the mechanisms of renal disease. We hope that this volume will help them in the management of patients with RPNG or in planning their research into this condition.