Recent Advances in Understanding Systemic Sclerosis

<p><span style=color: rgba(23 43 77 1)>Systemic sclerosis (SSc) is a complex multifaceted autoimmune disease characterized by vascular abnormalities immune system dysregulation and progressive fibrosis of the skin and internal organs. Despite significant strides in understanding the pathogenesis of SSc it remains a challenging condition to diagnose and manage due to its heterogeneity and its variability in clinical manifestations.</span></p><p><span style=color: rgba(23 43 77 1)>We are pleased to provide a comprehensive overview of the current state of knowledge treatment and future perspectives of therapeutic approaches in this Special Issue.</span></p>