<p>SAR focuses on the quantitative structure-activity relationship (QSAR) of the disposition and activities of various pharmacological groups – the first systematic approach for linking different side effects of drugs to their molecular structure and physiochemical properties.</p><p></p><p>This unique monograph describes the application of molecular modification to the practical improvement of therapeutic agents; depicts the quantitative measurement of biological activity as it relates to QSAR; provides essential guidance on selecting suitable mathematical models defining appropriate parameters in correlation studies and anticipating potential side effects during the tedious drug development process.</p>
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