Stereoselective Total Synthesis of the Natural Oxylipin

In this context we have developed a simple and straight forward synthesis of the natural oxylipin (6R7E9R10S)-6910-trihydroxyoctadeca-7-enoic acid. The starting materials were nonanal and 16-hexanediol and the key steps were Sharpless kinetic resolution asymmetric epoxidation and olefin cross metathesis. The reaction steps involved in the present synthesis are lesser compared to those required for the previous one.