<p>This guidance note provides a comprehensive overview of medical oxygen production distribution and use in Asia and the Pacific region and explores how to improve systems over the medium and long term. </p><p><br></p><p>It explains why surges in medical oxygen demand due to the COVID-19 pandemic have exacerbated deficiencies in oxygen systems. It highlights how greater coordination among stakeholders to plan and procure oxygen on a larger scale improve equipment and better train staff can dramatically benefit health systems and improve patient care.</p>