<p><span style=color: rgba(0 0 0 1)>Dear Colleagues</span></p><p><span style=color: rgba(0 0 0 1)>&nbsp;</span></p><p><span style=color: rgba(0 0 0 1)>Supramolecular systems (calixarenes cyclodextrins polymers peptides etc.) have attracted special attention due to their excellent therapeutic properties for biomedical applications such as gene and drug delivery. Numerous biomaterials-based supramolecular systems have been developed in the last decade for enhancing of biocompatibility and pharmacological activity. In particular supramolecular nanomaterials are considered a hot research topic because nanomedicine has become an interesting tool for the treatment of genetic diseases or cancer. Nevertheless novel systems and their properties are being continuously studied contributing to the development of efficient delivery systems.</span></p><p><span style=color: rgba(0 0 0 1)>&nbsp;</span></p><p><span style=color: rgba(0 0 0 1)>This Special Issue provides and highlights current progress in the use of the supramolecular systems for boosting gene and drug delivery. Preparation characterization and use of these systems as well as the latest developments in this research field are especially welcome.</span></p><p><span style=color: rgba(0 0 0 1)>&nbsp;</span></p><p><span style=color: rgba(0 0 0 1)>Authors are encorauged to submit original research articles and reviews in this promising research field.</span></p><p><span style=color: rgba(0 0 0 1)>&nbsp;</span></p><p><span style=color: rgba(0 0 0 1)>Dr. Francisco José Ostos</span></p><p><span style=color: rgba(0 0 0 1)>Dr. José Antonio Lebrón</span></p><p><span style=color: rgba(0 0 0 1)>Prof. Dr. Pilar López-Cornejo</span></p><p><span style=color: rgba(0 0 0 1)>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</span><em style=color: rgba(0 0 0 1)>Guest Editors</em></p>