<p>This book contains collections of selected articles presented at the SDEWES2021 conference and subsequently published in a special issue of <em>Sustainability</em>. The book provides state-of-the-art research overviewing practices in sustainable development energy water and environment systems as well as their uses and applications. Focus is given to waste management; higher biomass production; biorefineries; bio-digital interface and microbial fuel cells; energy and cost reduction in the building sector; and the economic impact of sustainability.&nbsp;</p>