This book is intended to be an introduction to pharmacy students regarding ''''Synthesis and Biological Aspects of Pyrimidine Derivatives''''. Pyrimidine and its derivatives are demonstrated as a pharmacologically active and important scaffold which possesses all kind of pharmacological activities such as analgesic anticonvulsant anti-depressive antipyretic sedative antiviral anti-HIV anti-inflammatory antimicrobial and anti-tumor activities. Upon completion of the course the students shall be able to know about the various types of pharmacological application and synthesis scheme for pyrimidines.