SYNTHESIS AND MOLECULAR MODELLING OF COUMARIN-THIAZOLE HYBRID SCAFFOLD

This book entitled SYNTHESIS AND MOLECULAR MODELLING OF COUMARIN-THIAZOLE HYBRID SCAFFOLDS AND EVALUATION OF ANTI-HEPATOCELLULAR CARCINOMA ACTIVITY is divided into 5 chapters. Coumarin is oxygen oxygen-containing heterocyclic compound in particular a benzopyrone class of compound containing a bicyclic lactone ring. Coumarin and its derivatives are well known due to their significance in the field of SCIENCE AND TECHNOLOGY. Besides coumarins thiazole and its derivatives have exhibited probable pharmacological properties. Based on the view of great scope and extensive applications of coumarin-thiazole hybrid scaffolds it drew attention to choose as a research topic. Coumarin-Thiazole extended with other heterocyclics has profound potency and key synthon for the auxiliary of new hetero cyclic compounds. An abundance of starting materials plenty of research evidence green pathways mild conditions and high scope for potential pharmacological applications are the added advantages of the research work. There is much scope to explore and extend coumarin-based research in the near future by upcoming researchers and science enthusiasts to get bright research findings.