Synthesis of Biologically Potent ��-Aminophosphonates

Amongst phosphorus compounds aminophosphonates and their derivatives have received considerable attention in recent years because they exhibit intriguing biological activities. α-aminophosphonate derivatives are gaining lot of importance in medicinal chemistry due to their applications as enzyme inhibitors pharmacological agents herbicides antibiotics and inhibitors of Excitatory Post- Synaptic Potential (EPSP) synthase and HIV Protease . α-Aminophosphonic acids seem to be even closer analogues of their α-amino phosphonic counter parts due to their monobasic/acidic character and higher stability of the P-C bond of phosphonicacids compared with the P-O bond. Due to its medicinal importance such as anti-cancer anti-HIV antithrombotic and antibacterial properties lot of reviews are needed to guide the reader into this fascinating aspect of phosphorus chemistry. This book has been initiated with this motto.