Synthesis of New Heterocyclic Compounds Starting from 2-Aminopyridine

The synthesis part of this work is divided into three different parts: Part One: This part involved the synthesis of 3-biphenyl-4-ylimidazo[12-a]pyridine [1] 3-phenylimidazo[12-a]pyridine [2] and other compounds directly from the starting material. Part Two: This part involved the synthesis of N-carbamoyl-N2-pyridin-2-ylglycinamid [12] N-(4-biphenyl-4-yl-13-oxazol-2-yl)-N2-pyridine -2-ylglyciamide [13] and other compounds from the reaction of 2-aminopyridine with ethylchloroacetate to yield ethyl-N-pyridin-2-ylglycinate [11] this compound was used as precursors. Part Three: This part involved the synthesis of 2-[(pyridine-2-ylamino)methyl]-45-dihydro-6H-134- oxadiazine-6-one [17] 3-[(pyridine-2-ylamino)methyl]16-dihydro-124- triazin-5(2H)-one [18] 5-[(pyridine-2-ylamino)methyl]-134-oxadiazole-2- thiol [19] and other compounds starting from 2-(pyridine-2-ylamino)acetohydrazide [16]. This compound was prepared from refluxing ethyl-N-pyridin-2-ylglycinate [11] with hydrazine hydrate.