The Gold Keys of Pyridone

The first part of this work reports the preparation of some αβ- unsaturated carbonyl compounds which are useful as starting materials to produce new different types of heterocyclic compounds. In this part of study we report the relation of 2-acetyl-naphthalene with some aldehydes to give the corresponding αβ- unsaturated carbonyl compounds (Ia-c). The condensation of these compounds with some carbon and/or nitrogen nucleophiles gave the appropriate pyridine pyrazole oxazole derivatives. Biological activity for the synthesized compounds have been studied for anticancer evaluation and antimicrobial activity.