Human Complement System in Health and Disease

<p>This authoritative single-source reference provides comprehensive examinations of the complement system-offering recent findings in basic science on the structure biology physiology and pathophysiology of complement proteins and the latest therapeutic approaches towards the control of complement-mediated diseases. <br>Written by over 40 international experts from North America Europe and Asia The Human Complement System in Health and Disease</p><li>describes the molecular architecture of the complement system <br> </li><li>details the structure of complement genes <br> </li><li>discusses gene organization as well as the topology and chemistry of ligand-binding sites and catalytic centers of complement proteins <br> </li><li>analyzes complement organization and activation including phylogeny and the newly discovered lectin pathway <br> </li><li>elucidates the regulation of complement gene expression and the structure and function of bioactive peptides <br> </li><li>explicates opsonic and immunoregulatory properties of complement fragments endothelial responses and interactions with viruses and bacteria <br> </li><li>and more!</li>