Liver disease is still a worldwide health problem. Unfortunately conventional or synthetic drugs used in the treatment of liver diseases caused serious side effects. This is one of the reasons for many people world widely to turn to complementary or alternative medicine.Recently the natural medical material of animal origin and pharmaceutical preparations on their basis as well as biologically active food supplements are the future medicine for diseases.Thereforethe present study selected Allolobophora caliginosa as natural supplement of animal origin to evaluate its efficacy against hepatotoxoicity induced by silicon dioxide nanoparticles.
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