Carbazole and its hybrid compounds were considered as very significant type of nitrogen containing heterocyclic compounds that are abundant in nature. The Carbazole moiety is constituent of a so many naturally occurring biologically active substances such as murrayafoline and carbazomycins. Numerous carbazole compounds such as oxazinocarbazoles benzocarbazoles pyridocarbazoles tetrahydrocarbazoles furo-carbazoles pyrrolocarbazoles oxazolinylcarbazoles indolocarbazoles thionocarbazoles imidazocarbazoles thiazolocarbazoles benzofurano-carbazoles benzopyrano-carbazoles.