TURA classification in chronic myeloid leukemia

Our retrospective and prospective study on the impact of the TURA classification on prognosis and survival in CML was carried out on a sample of 52 patients collected in the clinical haematology department of the Yopougon University Hospital over a 19-year period (1989 to 2008): Concerning the therapeutic response: In terms of haematological response and in a non-significant way (P = 0155) we observed a higher number of haematological response for the intermediate prognosis i.e. 27 cases against 2 cases for the good prognosis and 9 cases for the bad prognosis. Concerning the outcome: The number of deaths was low but not significantly (p = 0.122) with the TURA classification. We observed 7 cases of death for the intermediate prognosis 7 cases for the poor prognosis and 0 cases for the good prognosis. Concerning survival there was a significant difference in terms of median survival in the three groups p = 0.057. Thus for the good prognosis group the median survival was 40 months whereas for the intermediate and poor prognosis groups the median survival was 40 months.