What do twice-exceptional students and their parents teachers and guidance counselors identify as the supports and barriers for students with disabilities participating in Advanced Placement (AP) and/or College Level Learning classes? Thirty parents teachers and guidance counselors of twice-exceptional high school students participated in this study reporting about their perceptions and experiences. Six twice-exceptional college students who attended Advanced Placement and/or other for college credit classes while still in high school describe their experiences as well. Through a semi-structured interview process themes emerged indicating what helped twice-exceptional students to successfully participate in Advanced Placement and/or other for college credit classes and what barriers to participation they encountered along the way.