USE OF TRANEXAMIC ACID IN TOTAL KNEE ARTHROPLASTY

BackgroundThe antifibrinolytic tranexamic acid reduces surgical blood loss but studies have not identified an ideal route of administration.We tried to identify whether intra-articular route of administration of tranexamic acid is superior to its intravenous route of administration in reducing blood loss in post-operative period number of transfusion units and complications e.g. thromboembolic phenomenon and DVT.We prospectively compared the two routes of administration (I/A and I/V) in a study population of 28 patients. In all the patients staged bilateral TKA was performed one side receiving tranexamic acid I/A and the other I/V.