Allergy in the perioperative period is an important clinical problem. Unfortunately due to the lack of guidelines for the recognition and diagnosis of allergy/hypersensitivity there are still no epidemiological data on this issue. Hypersensitivity to anesthetic drugs remains a substantial hazard for patients at increased risk because it is difficult to promptly recognize; consequently the proper treatment may be delayed. In addition the lack of specific molecular markers for confirmation of anaphylaxis impedes accurate diagnosis.
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