Wound Healing in Periodontal Therapy

Wound healing is a complex highly regulated process that is critical in maintaining the barrier function of skin and is a mechanism whereby the body attempts to restore the integrity of the injured part. It is a summation of processes that follows injury and include coagulation inflammation matrix synthesis and deposition followed by angiogenesis fibroplasias epithelialization contraction remodeling and scar formation. Wound healing in the oral cavity is a complex process that involves interplay between oral cells and their extracellular matrixbacteriasaliva and gingival crevicular fluid. Periodontal tissues represent a unique system in the human body where epithelial soft and mineralized connective tissues come together to form a junction. Wound healing occupies an important field of research in modern biomedical science. The field has grown significantly over the past decade and the use of growth factors for application to periodontal and oral bone wounds is now a clinical reality.